Association of the RGS2 gene with extrapyramidal symptoms induced by treatment with antipsychotic medication.

@article{Greenbaum2007AssociationOT,
  title={Association of the RGS2 gene with extrapyramidal symptoms induced by treatment with antipsychotic medication.},
  author={Lior Greenbaum and Rael David Strous and Kyra Sarner Kanyas and Yifat Merbl and Anat Horowitz and Osnat Karni and Elena Katz and Moshe Kotler and Tsviya Olender and Smita Neelkanth Deshpande and Doron Lancet and Edna Ben-Asher and Bernard Lerer},
  journal={Pharmacogenetics and genomics},
  year={2007},
  volume={17 7},
  pages={519-28}
}
OBJECTIVES To investigate the role of genes encoding regulators of G protein signaling in early therapeutic response to antipsychotic drugs and in susceptibility to drug-induced extrapyramidal symptoms. As regulators of G protein signaling and regulators of G protein signaling-like proteins play a pivotal role in dopamine receptor signaling, genetically based, functional variation could contribute to interindividual variability in therapeutic and adverse effects. METHODS Consecutively… CONTINUE READING

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