Association of the PIK4CA schizophrenia-susceptibility gene in adults with the 22q11.2 deletion syndrome.

@article{Vorstman2009AssociationOT,
  title={Association of the PIK4CA schizophrenia-susceptibility gene in adults with the 22q11.2 deletion syndrome.},
  author={Jacob Vorstman and Eva W. C. Chow and Roel A. Ophoff and Herman van Engeland and Frits A. Beemer and Ren{\'e} S. Kahn and Richard J Sinke and Anne S. Bassett},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2009},
  volume={150B 3},
  pages={430-3}
}
The 22q11.2 deletion syndrome (22q11DS) is associated with an increased prevalence (20-30%) of schizophrenia. Therefore, it is likely that one or more genes within the 22q11.2 region are causally related to schizophrenia. Recently, a significant association with schizophrenia in the general population was reported for three SNPs in phosphatidyl-inositol-4-kinase-catalytic-alpha (PIK4CA), a gene located in the 22q11.2 region. In the current study, we tested the hypothesis that the same PIK4CA… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 11 references

Similar Papers

Loading similar papers…