Association of the Genetic Polymorphisms in Pre-MicroRNAs with Risk of Ischemic Stroke in a Chinese Population

@inproceedings{Huang2015AssociationOT,
  title={Association of the Genetic Polymorphisms in Pre-MicroRNAs with Risk of Ischemic Stroke in a Chinese Population},
  author={Suli Huang and Shiquan Zhou and Yanwei Oliver Zhang and Ziquan Lv and Shanshan Li and Changhui Xie and Yuebin Ke and Pingjian Deng and Yijie Geng and Qian Zhang and Xiaofan Chu and Zhaohui Yi and Ying Zhang and Tangchun Wu and Jin-quan Cheng},
  booktitle={PloS one},
  year={2015}
}
microRNA (miRNA) plays a role in the pathogenesis of ischemic stroke, and single nucleotide polymorphisms in miRNA genes may contribute to disease susceptibility. However, the effect of miR-146a, miR-196a2, and miR-499 polymorphisms on ischemic stroke susceptibility has been rarely reported. Using the TaqMan assay, we evaluated the association of hsa-miR-146a/rs2910164, hsa-miR-196a2/rs11614913, and hsa-miR-499/rs3746444 polymorphisms with the risk of ischemic stroke in a Chinese population… CONTINUE READING
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: A statement for healthcare professionals from the Stroke Council of the American Heart Association

  • EG Holliday, JM Maguire, TJ Evans, SA Koblar, J Jannes
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