Association of the ENPP1 K121Q polymorphism with susceptibility to type 2 diabetes in different populations: evidence based on 40 studies.

@article{Tang2014AssociationOT,
  title={Association of the ENPP1 K121Q polymorphism with susceptibility to type 2 diabetes in different populations: evidence based on 40 studies.},
  author={Song-tao Tang and Xin-Ru Shen and Hai-qin Tang and Chang-jiang Wang and Wei Wei and Qiu Yang Zhang and Yuan Wang},
  journal={Endocrine journal},
  year={2014},
  volume={61 11},
  pages={1093-103}
}
The K121Q gene polymorphism of ectoenzyme nucleotide pyrophosphate phosphodiesterase 1(ENPP1) has been widely investigated, however, results have been somewhat conflicting. The aim of this meta-analysis was to establish a precise estimation of the association between ENPP1 gene polymorphisms and type 2 diabetes (T2D). A literature search in PubMed, Embase, Cochrane Library and China Biology Medicine (CBM) databases was conducted on publications published prior to November 21(st), 2013. The… CONTINUE READING