Association of the DIO2 gene single nucleotide polymorphisms with recurrent depressive disorder.

@article{Gaecka2015AssociationOT,
  title={Association of the DIO2 gene single nucleotide polymorphisms with recurrent depressive disorder.},
  author={E. Gałecka and M. Talarowska and A. Orzechowska and P. G{\'o}rski and M. Bieńkiewicz and J. Szemraj},
  journal={Acta biochimica Polonica},
  year={2015},
  volume={62 2},
  pages={
          297-302
        }
}
Genetic factors may play a role in the etiology of depressive disorder. The type 2 iodothyronine deiodinase gene (DIO2) encoding the enzyme catalyzing the conversion of T4 to T3 is suggested to play a role in the recurrent depressive disorder (rDD). The current study investigates whether a specific single nucleotide polymorphism (SNP) of the DIO2 gene, Thr92Ala (T/C); rs 225014 or ORFa-Gly3Asp (C/T); rs 12885300, correlate with the risk for recurrent depression. Genotypes for these two single… Expand
9 Citations
Clinical significance of type 2 iodothyronine deiodinase polymorphism
  • 4

References

SHOWING 1-10 OF 55 REFERENCES
Association of genetic polymorphisms in the type II deiodinase gene with bipolar disorder in a subset of Chinese population
  • 41
Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians.
  • 32
Prevalence of Dio2T92A polymorphism and its association with thyroid autoimmunity
  • 11
A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters.
  • 93
  • Highly Influential
  • PDF
Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China
  • 81
  • PDF
Functional analysis of novel genetic variation in the thyroid hormone activating type 2 deiodinase.
  • 9
  • Highly Influential
  • PDF
The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe.
  • 94
  • PDF
...
1
2
3
4
5
...