Association of the AURKA and AURKC gene polymorphisms with an increased risk of gastric cancer.

@article{Mesic2016AssociationOT,
  title={Association of the AURKA and AURKC gene polymorphisms with an increased risk of gastric cancer.},
  author={Aner Mesic and Marija Rogar and Petra Hudler and Robert Juvan and Radovan Komel},
  journal={IUBMB life},
  year={2016},
  volume={68 8},
  pages={634-44}
}
Single nucleotide polymorphisms (SNPs) in mitotic checkpoint genes can contribute to susceptibility of human cancer, including gastric cancer (GC). We aimed to investigate the effects of Aurora kinase A (AURKA), Aurora kinase B (AURKB), and Aurora kinase C (AURKC) gene polymorphisms on GC risk in Slovenian population. We genotyped four SNPs in AURKA (rs2273535 and rs1047972), AURKB (rs2241909), and AURKC (rs758099) in a total of 128 GC patients and 372 healthy controls using TaqMan allelic… CONTINUE READING
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