Association of the 54-nucleotide repeat polymorphism of hPer3 with heroin dependence in Han Chinese population.

@article{Zou2008AssociationOT,
  title={Association of the 54-nucleotide repeat polymorphism of hPer3 with heroin dependence in Han Chinese population.},
  author={Yupei Zou and Ga Liao and Y-l Liu and Yong-Jun Wang and Zhi-rong Yang and Yi Lin and Yu-cun Shen and S-y Li and Jinling Xiao and Haiyan Guo and C Wan and Zhenhua Wang},
  journal={Genes, brain, and behavior},
  year={2008},
  volume={7 1},
  pages={26-30}
}
Circadian clock genes have the function of producing circadian rhythm. They are also implicated in the origin or development of many diseases such as cancers and neuropsychiatric diseases. The purpose of this study is to determine whether the 54-nucleotide repeat polymorphism of hPer3, one of the circadian clock genes, associates with heroin dependence. DNA samples were obtained from 209 Chinese heroin-dependent subjects and 249 Chinese healthy controls. The 54-nucleotide repeat polymorphism… CONTINUE READING