Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

@article{Hom2008AssociationOS,
  title={Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.},
  author={G. Hom and R. Graham and B. Modrek and K. Taylor and W. Ortmann and S. Garnier and Annette Lee and Sharon A. Chung and R. Ferreira and P. Pant and D. Ballinger and R. Kosoy and F. Demirci and M. Kamboh and A. Kao and C. Tian and I. Gunnarsson and A. Bengtsson and S. Rantap{\"a}{\"a}-Dahlqvist and M. Petri and S. Manzi and M. Seldin and L. R{\"o}nnblom and A. Syv{\"a}nen and L. Criswell and P. Gregersen and T. Behrens},
  journal={The New England journal of medicine},
  year={2008},
  volume={358 9},
  pages={
          900-9
        }
}
BACKGROUND Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in which the risk of disease is influenced by complex genetic and environmental contributions. Alleles of HLA-DRB1, IRF5, and STAT4 are established susceptibility genes; there is strong evidence for the existence of additional risk loci. METHODS We genotyped more than 500,000 single-nucleotide polymorphisms (SNPs) in DNA samples from 1311 case subjects with SLE and 1783 control subjects; all subjects were… Expand
High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
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TLDR
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Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
TLDR
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