Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

@article{Hom2008AssociationOS,
  title={Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.},
  author={G. Hom and R. Graham and B. Modrek and K. Taylor and W. Ortmann and S. Garnier and A. Lee and S. Chung and R. C. Ferreira and P. Pant and D. Ballinger and R. Kosoy and F. Demirci and M. Kamboh and A. Kao and C. Tian and I. Gunnarsson and A. Bengtsson and S. Rantap{\"a}{\"a}-Dahlqvist and M. Petri and S. Manzi and M. Seldin and L. R{\"o}nnblom and A. Syv{\"a}nen and L. Criswell and P. Gregersen and T. Behrens},
  journal={The New England journal of medicine},
  year={2008},
  volume={358 9},
  pages={
          900-9
        }
}
BACKGROUND Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in which the risk of disease is influenced by complex genetic and environmental contributions. Alleles of HLA-DRB1, IRF5, and STAT4 are established susceptibility genes; there is strong evidence for the existence of additional risk loci. METHODS We genotyped more than 500,000 single-nucleotide polymorphisms (SNPs) in DNA samples from 1311 case subjects with SLE and 1783 control subjects; all subjects were… Expand
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References

SHOWING 1-10 OF 61 REFERENCES
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus.
  • 939
  • PDF
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
  • 420
  • PDF
Genetics of human systemic lupus erythematosus: the emerging picture.
  • 164
...
1
2
3
4
5
...