Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.

@article{Rietveld1999AssociationOS,
  title={Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.},
  author={Anton G. Rietveld and S Neutz and Kai Simons and Steve Eaton},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 17},
  pages={12049-54}
}
In vertebrates, the formation of raft lipid microdomains plays an important part in both polarized protein sorting and signal transduction. To establish a system in which raft-dependent processes could be studied genetically, we have analyzed the protein and lipid composition of these microdomains in Drosophila melanogaster. Using mass spectrometry, we identified the phospholipids, sphingolipids, and sterols present in Drosophila membranes. Despite chemical differences between Drosophila and… CONTINUE READING
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657–659 Drosophila Rafts

  • R. G. Fehon, K. Johansen, I. Rebay, S. Artavanis-Tsakonas
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