Association of stem cell factor expression in nasal polyp epithelial cells with aspirin sensitivity and asthma.

@article{Kowalski2005AssociationOS,
  title={Association of stem cell factor expression in nasal polyp epithelial cells with aspirin sensitivity and asthma.},
  author={Marek L Kowalski and Anna Lewandowska-Polak and Jolanta Woźniak and Anetta Ptasinska and Andrzej W. Jankowski and Malgorzata Wagrowska-Danilewicz and M Danilewicz and Rafał Pawliczak},
  journal={Allergy},
  year={2005},
  volume={60 5},
  pages={631-7}
}
Mast cells constitute a significant proportion of cells infiltrating nasal polyp tissue, and epithelial cells may release stem cell factor (SCF), a cytokine with chemotactic and survival activity for mast cells. We aimed to assess the expression of SCF in human nasal polyp epithelial cells (NPECs) as related to patients' clinical phenotypes. Nasal polyp tissues were obtained from 29 patients [including nine with aspirin (ASA)-hypersensitivity and 12 with bronchial asthma] undergoing polypectomy… CONTINUE READING
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