Association of specific cytomegalovirus genotypes with death from myelosuppression after marrow transplantation.

@article{TorokStorb1997AssociationOS,
  title={Association of specific cytomegalovirus genotypes with death from myelosuppression after marrow transplantation.},
  author={Beverly J. Torok-Storb and Michael A. Boeckh and Christopher Hoy and Wendy W Leisenring and David H Myerson and Theodore A Gooley},
  journal={Blood},
  year={1997},
  volume={90 5},
  pages={2097-102}
}
A retrospective analysis of cytomegalovirus (CMV) genotype was conducted on 281 CMV isolates obtained from marrow transplant recipients. The genotyping was based on sequence variations in the gene encoding envelope glycoprotein B (gB) as detected by restriction analysis of polymerase chain reaction (PCR)-amplified gB DNA. Among all isolates studied, the distribution of gB types 1-4 was 48.4%, 16.4%, 24.6%, and 8.2%, respectively, with only 2.5% of all isolates containing more than one gB type… CONTINUE READING