Association of smoking and other risk factors with Fuchs' endothelial corneal dystrophy severity and corneal thickness.

@article{Zhang2013AssociationOS,
  title={Association of smoking and other risk factors with Fuchs' endothelial corneal dystrophy severity and corneal thickness.},
  author={Xiaolin Zhang and Robert P. Igo and Jeremy R Fondran and V. Vinod Mootha and Matt Oliva and Kristin M. Hammersmith and Alan Sugar and Jonathan H. Lass and Sudha K. Iyengar},
  journal={Investigative ophthalmology & visual science},
  year={2013},
  volume={54 8},
  pages={5829-35}
}
PURPOSE We investigated effects of smoking and other risk factors on the development of advanced Fuchs' endothelial corneal dystrophy (FECD) and on central corneal thickness (CCT). METHODS Eyes from Caucasian probands, affected and unaffected family members, and unrelated controls matched for age from the FECD Genetics Multi-Center Study (n = 2044 subjects) were examined. Univariate and multivariate models, adjusted for family correlations, were used to determine the effect of smoking, sex… CONTINUE READING

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