Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.

@article{Chen2009AssociationOS,
  title={Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.},
  author={Andrew H. Chen and Yongqiang Tang and Madhavi Rangaswamy and Jen Chyong Wang and Laura Almasy and Tatiana Foroud and Howard J. Edenberg and Victor M. Hesselbrock and JohnI. Nurnberger and Samuel Kuperman and Sean J. O'Connor and Marc A Schuckit and Lance O. Bauer and Jay A. Tischfield and John P. Rice and Laura J. Bierut and Alison M. Goate and Bernice Porjesz},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2009},
  volume={150B 3},
  pages={
          359-68
        }
}
Evidence suggests the P3 amplitude of the event-related potential and its underlying superimposed event-related oscillations (EROs), primarily in the theta (4-5 Hz) and delta (1-3 Hz) frequencies, as endophenotypes for the risk of alcoholism and other disinhibitory disorders. Major neurochemical substrates contributing to theta and delta rhythms and P3 involve strong GABAergic, cholinergic and glutamatergic system interactions. The aim of this study was to test the potential associations… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

Similar Papers

Loading similar papers…