Association of serum vitamin B12 levels with stage of liver fibrosis and treatment outcome in patients with chronic hepatitis C virus genotype 1 infection: a retrospective study

  title={Association of serum vitamin B12 levels with stage of liver fibrosis and treatment outcome in patients with chronic hepatitis C virus genotype 1 infection: a retrospective study},
  author={Nicolae-Catalin Mechie and Armin D Goralzcyk and Lars Reinhardt and Sabine Mihm and Ahmad Amanzada},
  journal={BMC Research Notes},
BackgroundChronic hepatitis C (CHC) is a global health challenge. New therapeutic agents with excellent sustained virological response (SVR) rates are available mainly in developed countries, while the majority of CHC patients live in countries with low health budget. Predictors of therapeutic response are therefore necessary. Vitamin B12 appears to be involved in hepatitis C virus replication.MethodsWe therefore studied retrospectively the relationship between baseline serum vitamin B12 levels… Expand
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