Association of serum periostin with aspirin-exacerbated respiratory disease.

@article{Kim2014AssociationOS,
  title={Association of serum periostin with aspirin-exacerbated respiratory disease.},
  author={Mi-Ae Kim and Kenji Izuhara and Shoichiro Ohta and Junya Ono and Moon Kyung Yoon and Ga Young Ban and Hye-Soo Yoo and Yoo Seob Shin and Young-Min Ye and Dong-ho Nahm and Hae-Sim Park},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  year={2014},
  volume={113 3},
  pages={
          314-20
        }
}
BACKGROUND Recent studies recommend periostin as a systemic biomarker of eosinophilic airway inflammation to predict responses to novel treatments that targets eosinophilic TH2-driven inflammation in asthmatic patients. OBJECTIVE To investigate the clinical implications of serum periostin levels in patients with aspirin-exacerbated respiratory disease (AERD) based on its overlapping TH2-mediated pathogenesis with the eosinophilic asthma. METHODS Serum periostin levels were measured by human… CONTINUE READING

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