Association of serial biochemical markers with acute ischemic stroke: the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator Stroke Study.

@article{Jauch2006AssociationOS,
  title={Association of serial biochemical markers with acute ischemic stroke: the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator Stroke Study.},
  author={Edward C. Jauch and Christopher J Lindsell and Joseph Broderick and Susan C Fagan and Barbara C. Tilley and S. R. Levine},
  journal={Stroke},
  year={2006},
  volume={37 10},
  pages={2508-13}
}
BACKGROUND AND PURPOSE Biochemical markers of acute neuronal injury may aid in the diagnosis and management of acute ischemic stroke. Serum samples from the National Institute for Neurological Disorders and Stroke (NINDS) recombinant tissue plasminogen activator Stroke Study were analyzed for the presence of 4 biochemical markers of neuronal, glial, and endothelial cell injury. These biochemical markers, myelin basic protein (MBP), neuron-specific enolase (NSE), S100beta, and soluble… CONTINUE READING