Association of prostate cancer risk alleles with unfavourable pathological characteristics in potential candidates for active surveillance.

@article{McGuire2012AssociationOP,
  title={Association of prostate cancer risk alleles with unfavourable pathological characteristics in potential candidates for active surveillance.},
  author={Barry B. McGuire and Brian T. Helfand and Shilajit D. Kundu and Qiaoyan Hu and Jessica A Banks and Phillip R. Cooper and William J. Catalona},
  journal={BJU international},
  year={2012},
  volume={110 3},
  pages={338-343}
}
OBJECTIVE • To assess whether the carrier status of 35 risk alleles for prostate cancer (CaP) is associated with having unfavourable pathological features in the radical prostatectomy specimen in men with clinically low risk CaP who fulfil commonly accepted criteria as candidates for active surveillance. PATIENTS AND METHODS • We studied men of European ancestry with CaP who fulfilled the commonly accepted clinical criteria for active surveillance (T1c, prostate-specific antigen <10 ng/mL… CONTINUE READING