Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes

@article{Butcher2013AssociationOP,
  title={Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes},
  author={Matthew J. Butcher and Daniel R. Hallinger and Eden Garcia and Yui Machida and Swarup K. Chakrabarti and Jerry L Nadler and Elena Vyacheslavovna Galkina and Yumi N. Imai},
  journal={Diabetologia},
  year={2013},
  volume={57},
  pages={491-501}
}
Chronic inflammation in type 2 diabetes is proposed to affect islets as well as insulin target organs. However, the nature of islet inflammation and its effects on islet function in type 2 diabetes remain unclear. Moreover, the immune cell profiles of human islets in healthy and type 2 diabetic conditions are undefined. We aimed to investigate the correlation between proinflammatory cytokine expression, islet leucocyte composition and insulin secretion in type 2 diabetic human islets. Human… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

Similar Papers

Loading similar papers…