Association of polymorphisms of the apolipoprotein B gene with coronary heart disease in Han Chinese.

@article{Ye1995AssociationOP,
  title={Association of polymorphisms of the apolipoprotein B gene with coronary heart disease in Han Chinese.},
  author={Ping Ye and Bao-sheng Chen and Shu-yu Wang},
  journal={Atherosclerosis},
  year={1995},
  volume={117 1},
  pages={43-50}
}
Four polymorphic sites of the apolipoprotein B (apo B) gene were investigated by using polymerase chain reaction (PCR) in 103 patients with coronary heart disease (CHD) and 100 age-matched healthy individuals selected from a population of Han Chinese in the Beijing area. The rare X+ allele of the XbaI restriction site was more frequently seen in CHD patients than in controls (0.088 vs. 0.025, P < 0.01). The relative frequency of rare E- allele of the EcoRI restriction site was significantly… CONTINUE READING
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