Association of polymorphisms in the beta2 and beta3 adrenoceptor gene with polycystic ovary syndrome.

@article{Kurabayashi2006AssociationOP,
  title={Association of polymorphisms in the beta2 and beta3 adrenoceptor gene with polycystic ovary syndrome.},
  author={Takumi Kurabayashi and Tetsuro Yahata and Jinhua Quan and Kenichi Tanaka},
  journal={The Journal of reproductive medicine},
  year={2006},
  volume={51 5},
  pages={389-93}
}
OBJECTIVE To investigate polymorphisms of the beta2 and beta3 adrenoceptor (BAR-2 and BAR-3, respectively) genes associated with insulin-resistant polycystic ovary syndrome (PCOS) pathogenesis. STUDY DESIGN Fifty-nine infertile Japanese women with PCOS and 97 healthy Japanese controls were studied. Blood metabolites and genomic DNA polymorphisms of BAR-2 (Arg16Gly and Gln27Glu) and BAR-3 (Trp64Arg) were analyzed. RESULTS The PCOS group had significantly higher weight, body mass index… CONTINUE READING