Association of polymorphisms in the ALOX15B gene with coronary artery disease.

@article{Wuest2014AssociationOP,
  title={Association of polymorphisms in the ALOX15B gene with coronary artery disease.},
  author={Sophia J. A. Wuest and Thomas Dag Horn and Jacqueline Marti-Jaun and Hartmut K{\"u}hn and Martin Hersberger},
  journal={Clinical biochemistry},
  year={2014},
  volume={47 6},
  pages={
          349-55
        }
}
BACKGROUND Atherosclerosis is a multifactorial disease and the underlying cause of coronary artery disease (CAD), myocardial infarction and stroke. Two main features are involved in the progression of atherosclerosis, lipid retention and inflammation. 12/15-lipoxygenases are involved in inflammation and have been implicated in atherosclerosis. Genetic association studies of the 15-lipoxygenase 1 (ALOX15) in humans revealed a neutral to atheroprotective role of the enzyme. Recently the epidermis… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 38 REFERENCES

Inflammation and immune regulation by 12/15-lipoxygenases.

  • Progress in lipid research
  • 2006
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Inflammation in atherosclerosis.

  • Arteriosclerosis, thrombosis, and vascular biology
  • 2012

Similar Papers

Loading similar papers…