Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.

Abstract

Toll-like receptors (TLRs) constitute a family of receptors directly recognizing a wide spectrum of exogenous and endogenous ligands playing the key role in realization of innate and adaptive immune response, and participating in the processes of cell proliferation, survival, apoptosis, angiogenesis, tissue remodeling and repair. Polymorphisms in TLR genes… (More)
DOI: 10.1016/j.humimm.2011.07.307

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