Association of plasminogen activator inhibitor-1 and vitamin D receptor expression with the risk of keloid disease in a Chinese population.

@article{Gong2017AssociationOP,
  title={Association of plasminogen activator inhibitor-1 and vitamin D receptor expression with the risk of keloid disease in a Chinese population.},
  author={Zhen-hua Gong and Jian-Feng Ji and Jun Yang and Tie Xiang and Chang-Kai Zhou and Xuan-liang Pan and Jian Yao},
  journal={The Kaohsiung journal of medical sciences},
  year={2017},
  volume={33 1},
  pages={24-29}
}
Keloid disease (KD) is a benign fibroproliferative scarring condition of unknown etiopathogenesis. Plasminogen activator inhibitor-1 (PAI-1) and vitamin D receptor (VDR) have been shown to play important roles in the progression of tissue fibrosis; therefore, both these genes are potential susceptibility genes for KD. We aimed to determine whether the gene expression levels of PAI-1 and VDR are altered in Chinese KD patients. We measured the expression of PAI and VDR in human peripheral blood… CONTINUE READING