Association of octyl-modified poly(acrylic acid) onto unilamellar vesicles of lipids and kinetics of vesicle disruption.

@article{Vial2005AssociationOO,
  title={Association of octyl-modified poly(acrylic acid) onto unilamellar vesicles of lipids and kinetics of vesicle disruption.},
  author={Florent Vial and Souad Rabhi and C Tribet},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2005},
  volume={21 3},
  pages={853-62}
}
Water-soluble polymers containing a few hydrophobic anchors are known to bind onto lipid vesicles and are used as stabilizers of liposome-based formulas. In contrast, polymers with high hydrophobicity destabilize the lipid bilayers. With macromolecules of intermediate hydrophobic/hydrophilic balance, a gradual sweep of the stabilization-destabilization capacity can be achieved and is considered as promising triggered systems for drug release, although the mechanism of permeabilization and… CONTINUE READING

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