Association of neonatal hyperbilirubinemia with uridine diphosphate-glucuronosyltransferase 1A1 gene polymorphisms: meta-analysis.

@article{Long2011AssociationON,
  title={Association of neonatal hyperbilirubinemia with uridine diphosphate-glucuronosyltransferase 1A1 gene polymorphisms: meta-analysis.},
  author={Jun Long and Shaofang Zhang and Xiaoyan Fang and Yuyuan Luo and Jiebo Liu},
  journal={Pediatrics international : official journal of the Japan Pediatric Society},
  year={2011},
  volume={53 4},
  pages={530-40}
}
BACKGROUND Recent reports have suggested that genetic factors, including mutations in the coding region or promoter of uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) may increase the risk of development of neonatal hyperbilirubinemia, but the relationship has not been evaluated on systematic review or meta-analysis. METHODS A meta-analysis of observational studies reporting effect estimates and 95% confidence intervals (95%CI) was conducted on the association between UGT1A1… CONTINUE READING

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