Association of nNOS and Rho-kinase with age-associated erectile dysfunction in Sprague-Dawley rats.

  title={Association of nNOS and Rho-kinase with age-associated erectile dysfunction in Sprague-Dawley rats.},
  author={Zhibo Ding and Xing-jie Shen and Yunfei Li},
  journal={Experimental and therapeutic medicine},
  volume={13 3},
The present study aimed to investigate the changes of Rho-associated kinase (Rho-kinase) and neuronal nitric oxide synthase (nNOS) expression in age-associated erectile dysfunction (ED) in Sprague-Dawley (SD) rats. A total of 100 intact male SD rats were divided into 20 groups according to their age (5-24 months; rats that were the same age in months were in the same group). Erectile response measurements were performed and the functional index intracavernosal pressure/mean arterial pressure… Expand
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