Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation.

@article{Kessels2000AssociationOM,
  title={Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation.},
  author={M. Kessels and {\AA}. E. Engqvist-Goldstein and D. Drubin},
  journal={Molecular biology of the cell},
  year={2000},
  volume={11 1},
  pages={
          393-412
        }
}
  • M. Kessels, Å. E. Engqvist-Goldstein, D. Drubin
  • Published 2000
  • Medicine, Biology
  • Molecular biology of the cell
  • Yeast Abp1p is a cortical actin cytoskeleton protein implicated in cytoskeletal regulation, endocytosis, and cAMP-signaling. We have identified a gene encoding a mouse homologue of Abp1p, and it is identical to SH3P7, a protein shown recently to be a target of Src tyrosine kinases. Yeast and mouse Abp1p display the same domain structure including an N-terminal actin-depolymerizing factor homology domain and a C-terminal Src homology 3 domain. Using two independent actin-binding domains, mAbp1… CONTINUE READING
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