Association of monocyte chemoattractant protein-1 (MCP-1)2518A/G polymorphism with proliferative diabetic retinopathy in northern Chinese type 2 diabetes

@article{Dong2014AssociationOM,
  title={Association of monocyte chemoattractant protein-1 (MCP-1)2518A/G polymorphism with proliferative diabetic retinopathy in northern Chinese type 2 diabetes},
  author={Li Dong and Xiao Lv and Bin Wang and Ye Qing Wang and Hua Mu and Zhuo Feng and Ping Liu},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2014},
  volume={252},
  pages={1921-1926}
}
The pathogenesis of proliferative diabetic retinopathy (PDR) remains poorly understood. Recent studies have implicated that monocyte chemoattractant protein-1 (MCP-1) is associated with diabetic microvascular or macrovascular complications. However, the relationship between single nucleotide polymorphism(SNP)c.2518A/G -rs1024611 in the MCP-1 gene with diabetic retinopathy remains controversial. In the present study, we evaluated the association of SNP in the MCP-1 gene with diabetic retinopathy… CONTINUE READING
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