Association of mitochondrial allele 4216C with increased risk for complicated sepsis and death after traumatic injury.


OBJECTIVES Numerous studies have linked impaired mitochondrial activity with increased risk for clinical complications after injury. Furthermore, a number of nonsynonymous polymorphisms have been identified within the mitochondrial genome that are believed to impair cellular respiration. These DNA variants include a nonsynonymous polymorphism (T4216C) in… (More)
DOI: 10.1097/TA.0b013e3181991ac8


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