Association of metabolic–bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants

@article{Syn2021AssociationOM,
  title={Association of metabolic–bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174 772 participants},
  author={Nicholas LX Syn and David E. Cummings and Louis Zizhao Wang and Daryl Jimian Lin and Joseph J. Zhao and Marie Loh and Zong Jie Koh and Claire Alexandra Zhen Chew and Ying Ern Loo and Bee Choo Tai and Guowei Kim and Jimmy Bok-Yan So and Lee M. Kaplan and John B. Dixon and Asim Shabbir},
  journal={The Lancet},
  year={2021},
  volume={397},
  pages={1830-1841}
}
Long-Term Cardiovascular Outcomes After Bariatric Surgery in the Medicare Population.
Effect of Bariatric Surgery on Survival and Hospitalizations in Patients with Severe Obesity. A Retrospective Cohort Study
TLDR
BS significantly reduced the risk of all-cause mortality and hospitalization after 10-year follow-up and when comparing hospitalization risk in the BS group only, a marked reduction after surgery was found for all BS types.
Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy
TLDR
Both SG and RYGB are safe procedures with significant long-term weight-loss, improvement of QOL and amelioration of comorbidities and remain below reference data from the general population at all timepoints.
Effects of Colchicine on Cardiovascular Outcomes in Patients with Coronary Artery Disease: A Systematic Review and One-Stage and Two-Stage Meta-Analysis of Randomized-Controlled Trials
TLDR
It is proposed that colchicine may be considered as an additional pharmacological adjunct to the first line therapy for patients with coronary artery disease.
The future of bariatric surgery research: A worldwide mapping of registered trials
TLDR
A systematic review of RCTs evaluating BS versus another surgical procedure or versus a medical control group, through a search in ClinicalTrials.gov found the most frequent outcomes to be investigated are obesity‐related diseases with the study of type 2 diabetes, followed by weight loss, quality of life, and surgical complications.
Seventy years of bariatric surgery: A systematic mapping review of randomized controlled trials
TLDR
It is revealed that much research in BS is wasted because of replication of RCTs on subjects for which there is already body of evidence, with small populations and follow‐up times mostly below 2 years.
Association of Weight Loss Achieved Through Metabolic Surgery With Risk and Severity of COVID-19 Infection.
TLDR
This cohort study found that, among patients with obesity, substantial weight loss achieved with surgery was associated with improved outcomes of COVID-19 infection, suggesting that obesity can be a modifiable risk factor for the severity of COIDs19 infection.
Nutritional Management in Bariatric Surgery Patients
TLDR
It is still debated whether it is necessary to lose weight prior to surgery, a procedure that can facilitate the surgeon's work reducing the surgical risk, but at the same time, lengthens preparation times increasing the risks associated with concomitant pathologies.
Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes (ARMMS‐T2D): Study rationale, design, and methods
TLDR
The Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes (ARMMS‐T2D) is a consortium of four randomized trials designed to compare long‐term efficacy and safety of surgery versus medical/lifestyle therapy on diabetes control and clinical outcomes.
Impact of preoperative weight loss achieved by gastric balloon on peri- and postoperative outcomes of bariatric surgery in super-obese patients: a retrospective matched-pair analysis
TLDR
A multi-stage therapeutic approach with gastric balloon prior to bariatric surgery in super-obese patients may be effective to facilitate safe surgery and should be considered when choosing the appropriate therapeutic regime and managing patients’ expectations.
...
...

References

SHOWING 1-10 OF 89 REFERENCES
Association between bariatric surgery and long-term survival.
TLDR
Those who underwent bariatric surgery compared with matched control patients who did not have surgery had lower all-cause mortality at 5 years and up to 10 years following the procedure, providing further evidence for the beneficial relationship between surgery and survival that has been demonstrated in younger, predominantly female populations.
Bariatric Surgery and Long-term Survival in Patients With Obesity and End-stage Kidney Disease.
TLDR
Among patients with obesity and end-stage kidney disease, bariatric surgery was associated with lower all-cause mortality compared with usual care and an increase in kidney transplant.
Association Between Bariatric Surgery and All-Cause Mortality: A Population-Based Matched Cohort Study in a Universal Health Care System
TLDR
Bariatric surgery was associated with substantially lower all-cause, cardiovascular, and cancer mortality and the lowered observed mortality of surgery was significant across most subgroups.
A 23-year study of mortality and development of co-morbidities in patients with obesity undergoing bariatric surgery (laparoscopic gastric banding) in comparison with medical treatment of obesity
TLDR
The preventive effect of LAGB on mortality is maintained up to 23 years, even with a decreased efficacy compared with the shorter-time study, while the preventive effect on co-morbidities and on hospital admissions increases with time.
Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials
TLDR
Compared with non-surgical treatment of obesity, bariatric surgery leads to greater body weight loss and higher remission rates of type 2 diabetes and metabolic syndrome and greater improvements in quality of life and reductions in medicine use.
Bariatric surgery, compared to medical treatment, reduces morbidity at all ages but does not reduce mortality in patients aged < 43 years, especially if diabetes mellitus is present: a post hoc analysis of two retrospective cohort studies
TLDR
The findings raise the question whether morbid obese patients should undergo BS as soon as possible, or whether patients might undergo surgery later in their life, as a result of the effect of aging.
Surgery Decreases Long-term Mortality, Morbidity, and Health Care Use in Morbidly Obese Patients
TLDR
This study shows that weight-loss surgery significantly decreases overall mortality as well as the development of new health-related conditions in morbidly obese patients.
Association of Bariatric Surgery Using Laparoscopic Banding, Roux-en-Y Gastric Bypass, or Laparoscopic Sleeve Gastrectomy vs Usual Care Obesity Management With All-Cause Mortality
TLDR
Among obese patients in a large integrated health fund in Israel, bariatric surgery using laparoscopic banding, gastric bypass, or Laparoscopic sleeve gastrectomy, compared with usual care nonsurgical obesity management, was associated with lower all-cause mortality over a median follow-up of approximately 4.5 years.
Potential Benefits and Harms of Gastric Bypass Surgery in Obese Individuals With Type 1 Diabetes: A Nationwide, Matched, Observational Cohort Study
TLDR
This observational study suggests bariatric surgery may yield similar benefits on risk for cardiovascular outcomes and mortality in patients with T1D and obesity as for patients with type 2 diabetes, however, some potential serious adverse effects suggest need for careful monitoring of such patients after surgery.
...
...