Association of meningococcal serotypes with the course of disease: serotypes 2a and 2b in the Netherlands, 1959-1981.

@article{Spanjaard1987AssociationOM,
  title={Association of meningococcal serotypes with the course of disease: serotypes 2a and 2b in the Netherlands, 1959-1981.},
  author={Lodewijk Spanjaard and P. Bol and Siem de Marie and H. C. Zanen},
  journal={The Journal of infectious diseases},
  year={1987},
  volume={155 2},
  pages={277-82}
}
Case histories of 692 patients with meningococcal disease due to serogroup B, C, or W (W-135) were reviewed to study the association of the serotypes 2a and 2b with the course of disease. The case-fatality rate in group B disease was significantly associated with serotype 2b (B:2b) strains (P = 0.03). Age and year of admission did not account for this association. Septicemia was also found more frequently with B:2b than with other B serotypes, but neurological complications and sequelae were… CONTINUE READING