Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis

@inproceedings{Huh2009AssociationOM,
  title={Association of mannose-binding lectin-2 genotype and serum levels with prognosis of sepsis},
  author={Jin Won Huh and Kyuyoung Song and Jung-Sun Yum and Sang-Bum Hong and Chae Man Lim and Younsuck Koh},
  booktitle={Critical care},
  year={2009}
}
INTRODUCTION Individuals deficient in mannose-binding lectin (MBL), an important component of the innate immune system, show increased susceptibility to infection. We investigated whether polymorphisms in the MBL2 gene and the serum level are associated with the severity and prognosis of sepsis. METHODS A total of 266 patients with sepsis and 398 healthy controls were enrolled. We analyzed the three single nucleotide polymorphisms (Gly54Asp, -550, and +4) in the MBL2 gene. Serum samples… CONTINUE READING
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