Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.

@article{Li2004AssociationOL,
  title={Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.},
  author={Yonghong Li and P. Nowotny and Peter Holmans and Scott Smemo and John S. K. Kauwe and Anthony L. Hinrichs and Kristina M. Tacey and Lisa M. Doil and Ryan van Luchene and Ver{\'o}nica Garc{\'i}a and Charles Rowland and Steve Schrodi and Diane Leong and Goran Gogic and Joanne Chung Yan Chan and Anibal Cravchik and David D. Ross and Kit Yu Lau and S. Kwok and Sheng-Yung Chang and Joe Catanese and J. Sninsky and Thomas J. White and John Hardy and John Powell and Simon Lovestone and John C. Morris and Leon Thal and Michael J Owen and Julie Williams and Alison M. Goate and Andrew Grupe},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 44},
  pages={15688-93}
}
Although several genes have been implicated in the development of the early-onset autosomal dominant form of Alzheimer's disease (AD), the genetics of late-onset AD (LOAD) is complex. Loci on several chromosomes have been linked to the disease, but so far only the apolipoprotein E gene has been consistently shown to be a risk factor. We have performed a large-scale single-nucleotide polymorphism (SNP)-based association study, across the region of linkage on chromosome 12, in multiple case… CONTINUE READING

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Genetic Data Analysis II (Sinauer, Sunderland, MA)

B. S. Weir
1996
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