Association of kidney dysfunction with silent lacunar infarcts and white matter hyperintensity in the general population: the Ohasama study.

@article{Otani2010AssociationOK,
  title={Association of kidney dysfunction with silent lacunar infarcts and white matter hyperintensity in the general population: the Ohasama study.},
  author={Harunori Otani and Masahiro Kikuya and Azusa Hara and Shiho Terata and Takayoshi Ohkubo and Takeo Kondo and Takuo Hirose and Taku Obara and Hirohito Metoki and Ryusuke Inoue and Kei Asayama and Atsuhiro Kanno and Hiroyuki Terawaki and M. Nakayama and Kazuhito Totsune and Haruhisa Hoshi and Hiroshi Satoh and Shin-Ichi Izumi and Yutaka Imai},
  journal={Cerebrovascular diseases},
  year={2010},
  volume={30 1},
  pages={43-50}
}
BACKGROUND No previous study has investigated the association of kidney dysfunction with silent lacunar infarcts and white-matter hyperintensity (WMH) independent of ambulatory blood pressure (BP). METHODS A cross-sectional study involving 1,008 participants (mean age 66 years) from a general population of Ohasama, Japan, was conducted. Calculated creatinine clearance (CCr) was estimated using the Cockcroft-Gault equation. In continuous and categorical analyses, the association between CCr… CONTINUE READING