Association of interleukin-4 gene polymorphisms with ischemic heart failure.

@article{Mahmoudi2014AssociationOI,
  title={Association of interleukin-4 gene polymorphisms with ischemic heart failure.},
  author={Mohammad Jafar Mahmoudi and Mona Hedayat and Mohammad Taghvaei and Ebrahim Nematipour and Elham Farhadi and Nilufar Esfahanian and Maryam Sadr and Maryam Mahmoudi and Keramat Nourijelyani and Ali Akbar Amirzargar and Nima Attaran Rezaei},
  journal={Cardiology journal},
  year={2014},
  volume={21 1},
  pages={24-8}
}
BACKGROUND As of the potential immunomodulatory effects of interleukin-4 (IL-4) and its importance in inhibiting the production of proinflammatory cytokines by monocytes and activated T cells, the IL-4 gene polymorphisms were investigated in a group of patients with chronic heart failure due to ischemic heart disease. METHODS Forty three patients with ischemic heart failure (IHF) were enrolled in this study and compared with 139 healthy individuals. The allele and genotype frequency of 3… CONTINUE READING
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