Association of interleukin 23 receptor variants with psoriatic arthritis.

  title={Association of interleukin 23 receptor variants with psoriatic arthritis.},
  author={Proton Rahman and Robert D. Inman and Walter P. Maksymowych and Jeff P. Reeve and Lynette Peddle and Dafna D Gladman},
  journal={The Journal of rheumatology},
  volume={36 1},
OBJECTIVE A recent genome-wide pooling study noted a significant association of interleukin 23 receptor (IL-23R) and psoriasis. Overxpression of IL-23 has been detected in lesional psoriatic skin, and induces epidermal proliferation. Given the interplay between psoriasis and PsA, we examined the association of IL-23R variants in 2 independent Canadian Caucasian cohorts of patients with psoriatic arthritis (PsA). METHODS We examined 496 PsA probands and 476 controls. Cases and controls were… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 25 extracted citations


Publications referenced by this paper.
Showing 1-10 of 15 references

SNPHAP: a program for estimating frequencies of large haplotypes of SNPs

  • D. Clayton
  • Internet. Available from:…
  • 2008

WHAP: SNP haplotype analysis package

  • S Purcell, P. Sham
  • Internet. Available from: http://pngu.mgh.harvard…
  • 2008

Quanto 1.1: A computer program for power and sample size calculations for genetic-epidemiology

  • WJ Gauderman, JM Morrison
  • Internet. Available from:…
  • 2006

TNF-a polymorphisms and risk of psoriatic arthritis

  • P Rahman, F Siannis, C Butt
  • Ann Rheum Dis 2006;65:919-23
  • 2006

Similar Papers

Loading similar papers…