Association of interleukin-1beta and interleukin-1 receptor antagonist polymorphisms with bacterial vaginosis in non-pregnant Italian women.

@article{Cauci2007AssociationOI,
  title={Association of interleukin-1beta and interleukin-1 receptor antagonist polymorphisms with bacterial vaginosis in non-pregnant Italian women.},
  author={Sabina Cauci and Manuela Di Santolo and Giorgia Casabellata and Kelli K. Ryckman and Scott Matthew Williams and Secondo Guaschino},
  journal={Molecular human reproduction},
  year={2007},
  volume={13 4},
  pages={
          243-50
        }
}
Bacterial vaginosis (BV) is the most prevalent alteration of vaginal microflora worldwide. BV is a polymicrobial disorder, and its etiology is elusive. Factors predisposing to this recurrent condition are not fully characterized. We aimed to investigate whether interleukin-1beta (IL-1beta) and IL-1 receptor antagonist (IL-1ra) polymorphisms are associated with BV in non-pregnant white Italian women. Genomic DNA was obtained from 164 BV positive, and 406 control women. Two diallelic… CONTINUE READING
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