Association of interleukin-1β genetic polymorphisms with cognitive performance in elderly females without dementia

@article{Sasayama2011AssociationOI,
  title={Association of interleukin-1β genetic polymorphisms with cognitive performance in elderly females without dementia},
  author={Daimei Sasayama and Hiroaki Hori and Toshiya Teraishi and Kotaro Hattori and Miho Ota and Junko Matsuo and Yumiko Kawamoto and Yukiko Kinoshita and Teruhiko Higuchi and Naoji Amano and Hiroshi Kunugi},
  journal={Journal of Human Genetics},
  year={2011},
  volume={56},
  pages={613-616}
}
Interleukin-1β (IL-1β) is considered to have a role in age-related cognitive decline. A recent study has shown that a promoter polymorphism of the IL-1β gene (rs16944) is associated with cognitive performance in elderly males without dementia. In this study, we examined whether polymorphisms of the IL-1β gene also influence cognitive functions in elderly females. Cognitive functions were assessed by the Wechsler adult intelligence scale-revised (WAIS-R) in 99 elderly (⩾60 years) females without… CONTINUE READING

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