Association of interferon‐γ and interferon regulatory factor 1 polymorphisms with asthma in a family‐based association study in Taiwan

  title={Association of interferon‐γ and interferon regulatory factor 1 polymorphisms with asthma in a family‐based association study in Taiwan},
  author={T. Wang and Y-T Chu and W-Y Chen and W. Feng and N-H Shih and C-H Hsiang and Y.-C. Ko},
  journal={Clinical & Experimental Allergy},
  • T. Wang, Y-T Chu, +4 authors Y.-C. Ko
  • Published 2006
  • Medicine
  • Clinical & Experimental Allergy
  • Background Asthma is a multi‐factorial disorder caused by complex interactions between genetic and environmental factors. IFN‐γ and IFN regulatory factor 1 (IRF‐1) affect Th1/Th2 cytokine balance, and influence the differentiation of Th2 cells, which influence the development of asthma. 
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