Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects

@article{Ramachandran2008AssociationOI,
  title={Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects},
  author={Vasudevan Ramachandran and Patimah Ismail and Johnson Stanslas and Norashikin Shamsudin and Saidi Moin and Rusni Mohd Jas},
  journal={Journal of the Renin-Angiotensin-Aldosterone System},
  year={2008},
  volume={9},
  pages={208 - 214}
}
Introduction. The deletion (D) allele of the angiotensin-converting enzyme (ACE) gene has been studied in various populations in relation to hypertension (HTN) and type 2 diabetes mellitus (T2DM) with contradictory results.This study sought to determine the association of insertion (I)/D polymorphism of the ACE gene in hypertensive andT2DM subjects in a Malaysian population. Materials and methods. A total of 260 subjects consisting of 65 HTN, 60 T2DM, 65 T2DM with HTN and 70 controls were… CONTINUE READING

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