Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men

@article{Vangipurapu2010AssociationOI,
  title={Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men},
  author={Jagadish Vangipurapu and Alena Stan{\vc}{\'a}kov{\'a} and Jussi Pihlajam{\"a}ki and Tiina Kuulasmaa and Teemu Kuulasmaa and Jussi Paananen and Johanna Kuusisto and Ele Ferrannini and Markku Laakso},
  journal={Diabetologia},
  year={2010},
  volume={54},
  pages={563-571}
}
Aims/hypothesisOf the confirmed type 2 diabetes susceptibility loci only a few are known to affect insulin sensitivity. We examined the association of indices of hepatic and adipocyte insulin resistance (IR) with 19 confirmed type 2 diabetes risk loci in a large population-based study.MethodsNon-diabetic participants (n = 8,460, age 57.3 ± 7.0 years, BMI 26.8 ± 3.8 kg/m2; mean ± SD) from a population-based cohort underwent an OGTT. Of them, 6,733 non-diabetic men were genotyped for single… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

Association of KCNJ 11 E 23 K ( rs 5219 ) polymorphism to Type 2 diabetes mellitus : a case-control study in Indian population of Eastern Uttar Pradesh

Sunita Singh, N K Agrawal, Gopeshwar Narayan
  • 2017
VIEW 4 EXCERPTS
HIGHLY INFLUENCED

Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans.

  • Liver international : official journal of the International Association for the Study of the Liver
  • 2015
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Power calculation for testing if disease is associated with marker in a case-control study using the GeneticsDesign package

W Qiu, R Lazarus
  • Available from http://bioconductor.org/packages/ release/bioc/html/GeneticsDesign.html. Accessed
  • 2010

A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1

A Haupt, M Guthoff, SA Schäfer
  • Lancet
  • 2009

Banting Lecture . From the triumvirate to the ominous octet : a new paradigm for the treatment of type 2

SM Grundy, JI Cleeman, Daniels
  • diabetes
  • 2009