Association of impaired diurnal blood pressure variation with a subsequent decline in glomerular filtration rate.

@article{Davidson2006AssociationOI,
  title={Association of impaired diurnal blood pressure variation with a subsequent decline in glomerular filtration rate.},
  author={Michael B. Davidson and John Kevin Hix and Donald G. Vidt and Daniel Brotman},
  journal={Archives of internal medicine},
  year={2006},
  volume={166 8},
  pages={846-52}
}
BACKGROUND Most healthy people exhibit a decrease in systolic blood pressure (SBP) at night. A drop of less than 10% from mean daytime values (nondipping) is associated with chronic kidney disease, insulin resistance, and cardiovascular events. Whether nondipping precedes a decline in renal function remains unclear. We hypothesized that nondipping would predict a decline in the glomerular filtration rate (GFR) over time. METHODS Consecutive patients referred for ambulatory blood pressure… CONTINUE READING
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