Association of immune recovery with hyperlipidaemia and apolipoprotein gene polymorphisms following highly active antiretroviral therapy in a cohort of Chinese HIV patients.

@article{Chan2016AssociationOI,
  title={Association of immune recovery with hyperlipidaemia and apolipoprotein gene polymorphisms following highly active antiretroviral therapy in a cohort of Chinese HIV patients.},
  author={Denise Pui-Chung Chan and Man-po Lee and Ngai Sze Wong and Ross Ka-kit Leung and Claire M. Naftalin and Shui Shan Lee},
  journal={BMJ open},
  year={2016},
  volume={6 4},
  pages={
          e010998
        }
}
OBJECTIVE To examine the associations between CD4 recovery, dyslipidaemia and apolipoprotein (APO) gene single nucleotide polymorphisms (SNPs) following highly active antiretroviral therapy (HAART). DESIGN Retrospective observational cohort study. SETTING A major HIV care clinic in Hong Kong. PARTICIPANTS 197 Chinese treatment-naïve HIV patients. OUTCOME MEASURES Maximum CD4 count and its rise 2-3 years after HAART initiation and their association with abnormal total cholesterol (TC… CONTINUE READING

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