Association of heparanase gene (HPSE-1) single nucleotide polymorphisms with gastric cancer.

@article{Yue2010AssociationOH,
  title={Association of heparanase gene (HPSE-1) single nucleotide polymorphisms with gastric cancer.},
  author={Zhenyu Yue and Yongxi Song and Zhenning Wang and Yang Luo and Li Jiang and Lili Xing and Huimian Xu and Xue Zhang},
  journal={Journal of surgical oncology},
  year={2010},
  volume={102 1},
  pages={68-72}
}
BACKGROUND Heparanase activity plays a decisive role in biological processes associated with remodeling of the extracellular matrix (e.g., cancer metastasis, angiogenesis, and inflammation). Heparanase gene overexpression has been associated with advanced stage and poor survival in several cancers. We investigated the potential association between single nucleotide polymorphisms (SNPs) of the HPSE-1 gene, tumor susceptibility, clinicopathological parameters, and survival with gastric cancer… CONTINUE READING
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