Association of helicobacter pylori CagA translocation with the expression of CagA-signaling transduction molecules in gastric mucosa-associated lymphoid tissue lymphoma

@inproceedings{Kuo2014AssociationOH,
  title={Association of helicobacter pylori CagA translocation with the expression of CagA-signaling transduction molecules in gastric mucosa-associated lymphoid tissue lymphoma},
  author={Sung-hsin Kuo and Li Chen and Chung-Hui Lin and Ping-Ning Hsu and Ming-Shiang Wu and Hui-Jen Tsai and Y. S. Tzeng and Kun-Huei Yeh and Ann-Lii Cheng},
  year={2014}
}
8571 Background: We previously reported that a direct contact of Helicobacter pylori (HP) with B cells results in CagA translocation into the latter, and the translocated CagA regulates intracellular signaling pathways. Toward this end, we recently found that CagA do exist in the malignant B cells of gastric mucosa-associated lymphoid tissue (MALT) lymphoma, and its presence is closely associated with HP-dependence. In this study, we further evaluate whether CagA expression regulates signaling… CONTINUE READING