Association of glucokinase regulatory gene polymorphisms with risk and severity of non-alcoholic fatty liver disease: an interaction study with adiponutrin gene

@article{Tan2013AssociationOG,
  title={Association of glucokinase regulatory gene polymorphisms with risk and severity of non-alcoholic fatty liver disease: an interaction study with adiponutrin gene},
  author={H M Tan and Shamsul Mohd Zain and Rosmawati Mohamed and Sanjay Rampal and K Chin and Roma Choudhury Basu and Phaik-Leng Cheah and Sanjiv Mahadeva and Zahurin Mohamed},
  journal={Journal of Gastroenterology},
  year={2013},
  volume={49},
  pages={1056-1064}
}
Recent genome-wide association studies demonstrated an association between single nucleotide polymorphisms (SNPs) on the glucokinase regulatory gene (GCKR) with hepatic steatosis. This study attempted to investigate the association of GCKR rs780094 and rs1260326 with susceptibility to non-alcoholic fatty liver disease (NAFLD) and its severity. The genotypes were assessed on 144 histologically confirmed NAFLD patients and 198 controls using a Sequenom MassARRAY platform. The GCKR rs1260326 and… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS