Association of glomerular filtration rate on presentation with subsequent mortality in non-ST-segment elevation acute coronary syndrome; observations in 13,307 patients in five TIMI trials.

@article{Gibson2004AssociationOG,
  title={Association of glomerular filtration rate on presentation with subsequent mortality in non-ST-segment elevation acute coronary syndrome; observations in 13,307 patients in five TIMI trials.},
  author={C Michael Gibson and Raphaelle L Dumaine and Eli V. Gelfand and Sabina A. Murphy and David A. Morrow and Stephen D. Wiviott and Robert P Giugliano and Christopher Paul Cannon and Elliott Marshall Antman and Eugene Braunwald},
  journal={European heart journal},
  year={2004},
  volume={25 22},
  pages={1998-2005}
}
AIMS To determine the association of glomerular filtration rate (GFR) with clinical outcomes in the setting of non-ST-segment elevation acute coronary syndromes (NSTE-ACS). METHODS AND RESULTS Data were pooled from five NSTE-ACS TIMI trials (TIMI 11A and B, TIMI 12, OPUS-TIMI 16 and TACTICS-TIMI 18) and were available in 13 307 patients. GFR was assessed as a continuous and a categorical variable (normal: > or = 90 mL/min/1.73 m2, n=4952; mildly decreased: 60-89 mL/min/1.73 m2, n=6262; and… CONTINUE READING

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