Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations.

@article{Nakata2012AssociationOG,
  title={Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations.},
  author={I. Nakata and K. Yamashiro and Yumiko Akagi-Kurashige and M. Miyake and K. Kumagai and A. Tsujikawa and K. Liu and L. Chen and D. T. Liu and T. Lai and Yoichi Sakurada and Seigo Yoneyama and Ching-Yu Cheng and P. Cackett and I. Yeo and W. Tay and B. Cornes and E. Vithana and T. Aung and K. Matsuo and F. Matsuda and T. Wong and H. Iijima and C. Pang and N. Yoshimura},
  journal={Investigative ophthalmology \& visual science},
  year={2012},
  volume={53 10},
  pages={
          6576-81
        }
}
PURPOSE To evaluate the association of genetic variants at chromosomes 8p21 and 4q12 with the risk of developing AMD and its two main subtypes, choroidal neovascular membrane (CNV) and polypoidal choroidal vasculopathy (PCV), in Asian populations. METHODS The study population comprised 2360 patients with neovascular AMD (1013 typical AMD-CNV and 1282 PCV), and 3598 controls from four independent cohorts, two of Japanese (n = 4859) and two of Chinese (n = 1099) ethnicity. We performed a meta… Expand
The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye.
Association of Genetic Variants with Polypoidal Choroidal Vasculopathy: A Systematic Review and Updated Meta-analysis.
TNFRSF10A-LOC389641 rs13278062 but not REST-C4orf14-POLR2B-IGFBP7 rs1713985 was found associated with age-related macular degeneration in a Chinese population.
...
1
2
3
...

References

SHOWING 1-10 OF 37 REFERENCES
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration.
...
1
2
3
4
...