Association of genetic variants of cancer stem cell gene CD44 haplotypes with gallbladder cancer susceptibility in North Indian population

@article{Sharma2013AssociationOG,
  title={Association of genetic variants of cancer stem cell gene CD44 haplotypes with gallbladder cancer susceptibility in North Indian population},
  author={Kiran Lata Sharma and Anu Yadav and Annapurna Gupta and Sonam Tulsayan and Vijay Kumar and Sanjeev Misra and Ashok Kumar and Balraj Mittal},
  journal={Tumor Biology},
  year={2013},
  volume={35},
  pages={2583-2589}
}
CD44 is an important marker for cancer stem cells. Germline variants in CD44 gene have been associated with susceptibility to breast and nasopharyngeal carcinomas but no study in gallbladder cancer (GBC) has been done yet. The present study included 405 GBC patients and 200 healthy controls from North India. Tagger SNPs for CD44 were selected from the GIH population data. Genotyping was carried out by PCR-RFLP and Taqman probes. Statistical analysis was done by SPSS. Bonferroni correction was… CONTINUE READING
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