Association of genetic polymorphisms of ACADSB and COMT with human hypertension

@article{Kamide2007AssociationOG,
  title={Association of genetic polymorphisms of ACADSB and COMT with human hypertension},
  author={K. Kamide and Y. Kokubo and Jing Yang and T. Matayoshi and N. Inamoto and S. Takiuchi and T. Horio and Y. Miwa and M. Yoshii and H. Tomoike and C. Tanaka and Mariko Banno and T. Okuda and Y. Kawano and T. Miyata},
  journal={Journal of Hypertension},
  year={2007},
  volume={25},
  pages={103–110}
}
Objectives Genetically hypertensive rats provide an excellent model to investigate the genetic mechanisms of hypertension. We previously identified three differentially expressed genes, Acadsb (short/branched chain acyl-CoA dehydrogenase), Comt (catecholamine-O-methyltransferase), and Pnpo (pyridoxine 5′-phosphate oxidase), in hypertensive and normotensive rat kidneys as potential susceptibility genes for rat hypertension. We examined the association of human homologues of these genes with… Expand
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